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Division of Nephrology, Hypertension & Renal Transplantation Department of Medicine in the College of Medicine
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Education Overview

The Enigma of APOL1 and Kidney Disease in African Americans: Where Do We Stand Today? Rupam Ruchi, MD (W-0012)

You can watch the video lecture using the link below. After watching the video, return to this page to take the quiz and survey for credit.

https://youtu.be/EysjKOcll9M

YouTube CME Channel

Presented by
Rupam Ruchi, MD
Clinical Assistant Professor
UF Division of Nephrology, Hypertension & Renal Transplantation

Target Audience
Physicians, Fellows, Residents, Students

Program Description
This CME activity consists of an educational component (slides, audio lecture) in an electronic format, followed by an online post-test. Estimated time to complete this activity, including review of materials, is 1.75 hours.

Requirements for Successful Completion

  • This CME activity consists of an educational component (audio lecture in an electronic format, which is followed by an online post-test).
  • Certificates are awarded upon successful completion (80% proficiency) of the post-test.
  • In order to receive credit, participants must view the presentation in its entirety.
  • The University of Florida College of Medicine will report CME credit to CE Broker when applicable.
  • There is no fee to participate in this CME activity or to receive CME credit.

Learning Objectives
As a result of participation in this activity, participants should be able to:

  • Assess the association of APOL1 with kidney disease in African Americans.
  • Illustrate the evolution of APOL1 in patients.
  • Express the biology of African Americans with APOL1.

Faculty Disclosure
Rupam Ruchi has disclosed that she has no relevant financial disclosures. No one else in a position to control content has any financial relationships to disclose.

Continuing Medical Education Credit
Accreditation: The University of Florida College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit: The University of Florida College of Medicine designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Release Date: March 24, 2016

Expiration Date: March 24, 2017

 

CME Course Credit Registration W-0012

Name(Required)
Address(Required)

Quiz

You must score 80% in order to receive a passing grade and CME credit for the course.
1. What gene is highly associated with kidney disease in African Americans?(Required)
2. What kind of kidney disease in AA, is this gene not implicated in?(Required)
3. What advantage do the two risk alleles confer in this population?(Required)
4. What does the latest evidence show with respect to mechanism of cellular cytotoxicity of APOL1 risk alleles?(Required)
5. What is the prevalance of two risk alleles in AA population?(Required)
6. In addition to humans, which organism have the APOL1 gene(Required)
7. Which of the following statements is true about APOL1 null allele?(Required)
8. Which is one of the proposed candidates for a "second hit" for development of kidney disease in those with 2 APOL1 risk alleles(Required)
9. What type of Kidney disease is APOL1 risk alleles most strongly associated with?(Required)
10. What cells in the human kidney, stain highly positive for APOL1?(Required)

Please fill out the CME Evaluation Survey upon completion of this course.

You will receive a confirmation email with additional information approving your course credit.