Azra Bihorac, M.D., MS FCCM, FASN
Senior Associate Dean For Research Affairs At The University Of Florida College Of Medicine; Professor Of Medicine, Surgery And Anesthesiology; Director, Intelligent Clinical Care Center
Department:
MD-MED QUANTITATIVE HEALTH
Business Phone:
(352) 273-5995
About Azra Bihorac
I grew up in a region of northern Bosnia known for a disease called Balkan endemic nephropathy, or BEN, which causes kidney failure. My career in nephrology really began from wanting to help people from my home town suffering from kidney ailments.
I am the senior associate dean of the Office of Research in the University of Florida College of Medicine. I am also the R. Glenn Davis Professor of Medicine, Surgery, Anesthesiology and Physiology & Functional Genomics, and director of the Intelligent Clinical Care Center IC3 at UF. IC3 is a multidisciplinary center focused on developing and providing sustainable support and leadership for transformative medical AI research, education, and clinical applications to advance patients’ health in critical and acute care medicine. The center uses the extensive repository of clinical and research data from UF Health, one of Florida’s largest health care systems, to support unprecedented, world-leading artificial intelligence research and innovation for transforming the diagnosis, monitoring and treatment for critically and acutely ill patients.
My vision is to develop tools for intelligent human-centered health care that delivers optimized care tailored to a patient’s “personal clinical profile” using digital data. Through my work in national and international professional organizations in nephrology and critical care medicine, I advocated for women physicians and scientists, promoting their equality and recognition in health care leadership, research and education. With the help of patients and providers alike, I believe we can create medical AI that is trustworthy and ethical.
I earned my medical degree at the University of Sarajevo School of Medicine in Sarajevo, Bosnia and Herzegovina. Then, I completed my nephrology fellowship, internal medicine residency and critical care medicine fellowship at the University of Florida. Finally, I earned my Master of Science in clinical science at UF in 2011.
I have over 200 peer-reviewed articles with more than 10,000 citations. In addition to my research, I have received notable awards from the Society of Critical Care Medicine and funding from the National Institutes of Health since 2010.
In my free time, I like hanging out with my family, reading and having discussions with my book club and traveling, nationally and internationally.
Related Links:
Teaching Profile
Courses Taught
2018
MDT7090 Elective Topics
2012-2014
BMS4905 Medical Sciences Senior Research
2011,2014
PHC7979 Advanced Research
2009
IDH4917 Undergrad Research
Board Certifications
-
Clinical InformaticsAmerican Board of Preventive Medicine
-
Critical Care MedicineAmerican Board of Internal Medicine
-
Internal MedicineAmerican Board of Internal Medicine
-
NephrologyAmerican Board of Internal Medicine
-
Neurocritical CareUnited Council of Neurological Subspecialty
Clinical Profile
Specialties
- Nephrology
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-5745-2863
Publications
2023
A deep learning–based dynamic model for predicting acute kidney injury risk severity in postoperative patients
Surgery.
174(3):709-714
[DOI] 10.1016/j.surg.2023.05.003.
2023
A Systematic Review on Participant Diversity in Clinical Trials-Have We Made Progress for the Management of Obesity and Its Metabolic Sequelae in Diet, Drug, and Surgical Trials.
Journal of racial and ethnic health disparities.
10(6):3140-3149
[DOI] 10.1007/s40615-022-01487-0.
[PMID] 36536164.
2023
Artificial intelligence guidance of advanced heart failure therapies: A systematic scoping review.
Frontiers in cardiovascular medicine.
10
[DOI] 10.3389/fcvm.2023.1127716.
[PMID] 36910520.
2023
Bilateral renal artery stenosis impacts postoperative complications after major vascular surgery.
Surgery open science.
14:17-21
[DOI] 10.1016/j.sopen.2023.06.001.
[PMID] 37409074.
2023
Building an automated, machine learning-enabled platform for predicting post-operative complications.
Physiological measurement.
44(2)
[DOI] 10.1088/1361-6579/acb4db.
[PMID] 36657179.
2023
Challenges in Pharmacovigilance: Variability in the Criteria for Determining Drug-Associated Acute Kidney Injury in Retrospective, Observational Studies.
Nephron.
1-8
[DOI] 10.1159/000531916.
[PMID] 37607496.
2023
Clinical Considerations for Patients Experiencing Acute Kidney Injury Following Percutaneous Nephrolithotomy
Biomedicines.
11(6)
[DOI] 10.3390/biomedicines11061712.
[PMID] 37371807.
2023
Clinical courses of acute kidney injury in hospitalized patients: a multistate analysis.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-45006-5.
[PMID] 37853103.
2023
Clinical Courses of Acute Kidney Injury in Hospitalized Patients: A Multistate Analysis.
ArXiv.
[PMID] 36945689.
2023
Computable Phenotypes to Characterize Changing Patient Brain Dysfunction in the Intensive Care Unit.
ArXiv.
[PMID] 36945691.
2023
Continuous ECG monitoring should be the heart of bedside AI-based predictive analytics monitoring for early detection of clinical deterioration.
Journal of electrocardiology.
76:35-38
[DOI] 10.1016/j.jelectrocard.2022.10.011.
[PMID] 36434848.
2023
Digital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup
Nature Reviews Nephrology.
19(12):807-818
[DOI] 10.1038/s41581-023-00744-7.
2023
Digital Health Transformers and Opportunities for Artificial Intelligence–Enabled Nephrology
Clinical Journal of the American Society of Nephrology.
18(4):527-529
[DOI] 10.2215/cjn.0000000000000085.
2023
Dynamic predictions of postoperative complications from explainable, uncertainty-aware, and multi-task deep neural networks
Scientific Reports.
13(1)
[DOI] 10.1038/s41598-023-27418-5.
[PMID] 36681755.
2023
Machine Learning–Enabled Clinical Information Systems Using Fast Healthcare Interoperability Resources Data Standards: Scoping Review
JMIR Medical Informatics.
11:e48297-e48297
[DOI] 10.2196/48297.
[PMID] 37646309.
2023
Moving toward a contemporary classification of drug-induced kidney disease.
Critical care (London, England).
27(1)
[DOI] 10.1186/s13054-023-04720-2.
[PMID] 37946280.
2023
Overtriage, Undertriage, and Value of Care after Major Surgery: An Automated, Explainable Deep Learning-Enabled Classification System.
Journal of the American College of Surgeons.
236(2):279-291
[DOI] 10.1097/XCS.0000000000000471.
[PMID] 36648256.
2023
Persistent Acute Kidney Injury is Associated with Poor Outcomes and Increased Hospital Cost in Vascular Surgery.
Annals of vascular surgery.
[DOI] 10.1016/j.avsg.2023.06.023.
[PMID] 37423327.
2023
Postoperative Overtriage to an Intensive Care Unit Is Associated With Low Value of Care.
Annals of surgery.
277(2):179-185
[DOI] 10.1097/SLA.0000000000005460.
[PMID] 35797553.
2023
Postoperative Triage Hybrid Model: In Reply to Bellini and Bignami.
Journal of the American College of Surgeons.
237(2)
[DOI] 10.1097/XCS.0000000000000747.
[PMID] 37184098.
2023
Predictive Modeling for Readmission to Intensive Care: A Systematic Review.
Critical care explorations.
5(1)
[DOI] 10.1097/CCE.0000000000000848.
[PMID] 36699252.
2023
Reinforcement Learning for Clinical Applications
Clinical Journal of the American Society of Nephrology.
18(4):521-523
[DOI] 10.2215/cjn.0000000000000084.
2023
Resource use for cholecystectomy with versus without cholangiography: A multicenter, propensity-matched analysis.
Surgery.
174(2):152-158
[DOI] 10.1016/j.surg.2023.04.027.
[PMID] 37188579.
2023
The persistent inflammation, immunosuppression, and catabolism syndrome 10 years later.
The journal of trauma and acute care surgery.
95(5):790-799
[DOI] 10.1097/TA.0000000000004087.
[PMID] 37561664.
2023
Utilization of the percutaneous left ventricular support as bridge to heart transplantation across the United States: In-depth UNOS database analysis
The Journal of Heart and Lung Transplantation.
42(11):1597-1607
[DOI] 10.1016/j.healun.2023.06.002.
2022
Aligning Patient Acuity With Resource Intensity After Major Surgery: A Scoping Review.
Annals of surgery.
275(2):332-339
[DOI] 10.1097/SLA.0000000000005079.
[PMID] 34261886.
2022
Artificial Intelligence for AKI!Now: Let’s Not Await Plato’s Utopian Republic
Kidney360.
3(2):376-381
[DOI] 10.34067/kid.0003472021.
2022
Artificial intelligence-enabled decision support in nephrology
Nature Reviews Nephrology.
18(7):452-465
[DOI] 10.1038/s41581-022-00562-3.
[PMID] 35459850.
2022
Characterization and Outcomes of Hospitalized Children With Coronavirus Disease 2019: A Report From a Multicenter, Viral Infection and Respiratory Illness Universal Study (Coronavirus Disease 2019) Registry.
Critical care medicine.
50(1):e40-e51
[DOI] 10.1097/CCM.0000000000005232.
[PMID] 34387240.
2022
Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis: A Prospective Observational Study.
Annals of surgery.
275(6):1184-1193
[DOI] 10.1097/SLA.0000000000004360.
[PMID] 33196489.
2022
Early Biomarker Signatures in Surgical Sepsis
Journal of Surgical Research.
277:372-383
[DOI] 10.1016/j.jss.2022.04.052.
[PMID] 35569215.
2022
EARLY DIFFERENTIATION BETWEEN SEPSIS AND STERILE INFLAMMATION VIA URINARY GENE SIGNATURES OF METABOLIC DYSREGULATION.
Shock (Augusta, Ga.).
58(1):20-27
[DOI] 10.1097/SHK.0000000000001952.
[PMID] 35904146.
2022
Executive summary of the artificial intelligence in surgery series
Surgery.
171(5):1435-1439
[DOI] 10.1016/j.surg.2021.10.047.
[PMID] 34815097.
2022
Federated learning for preserving data privacy in collaborative healthcare research.
Digital health.
8
[DOI] 10.1177/20552076221134455.
[PMID] 36325438.
2022
Gamification for Machine Learning in Surgical Patient Engagement.
Frontiers in surgery.
9
[DOI] 10.3389/fsurg.2022.896351.
[PMID] 35656082.
2022
Ideal algorithms in healthcare: Explainable, dynamic, precise, autonomous, fair, and reproducible
PLOS Digital Health.
1(1)
[DOI] 10.1371/journal.pdig.0000006.
[PMID] 36532301.
2022
Methods for Phenotyping Adult Patients in Sepsis and Septic Shock: A Scoping Review.
Critical care explorations.
4(4)
[DOI] 10.1097/CCE.0000000000000672.
[PMID] 35372844.
2022
Multi-dimensional patient acuity estimation with longitudinal EHR tokenization and flexible transformer networks.
Frontiers in digital health.
4
[DOI] 10.3389/fdgth.2022.1029191.
[PMID] 36440460.
2022
Older Adults Demonstrate Biomarker Evidence of the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PICS) After Sepsis.
The journals of gerontology. Series A, Biological sciences and medical sciences.
77(1):188-196
[DOI] 10.1093/gerona/glab080.
[PMID] 33721883.
2022
Performance of a Machine Learning Algorithm Using Electronic Health Record Data to Predict Postoperative Complications and Report on a Mobile Platform.
JAMA network open.
5(5)
[DOI] 10.1001/jamanetworkopen.2022.11973.
[PMID] 35576007.
2022
Performance of a Standardized Clinical Assay for Urinary C-C Motif Chemokine Ligand 14 (CCL14) for Persistent Severe Acute Kidney Injury.
Kidney360.
3(7):1158-1168
[DOI] 10.34067/KID.0008002021.
[PMID] 35919538.
2022
Personalized decision-making for acute cholecystitis: Understanding surgeon judgment.
Frontiers in digital health.
4
[DOI] 10.3389/fdgth.2022.845453.
[PMID] 36339515.
2022
Phenotype clustering in health care: A narrative review for clinicians.
Frontiers in artificial intelligence.
5
[DOI] 10.3389/frai.2022.842306.
[PMID] 36034597.
2022
Physiologic signatures within six hours of hospitalization identify acute illness phenotypes
PLOS Digital Health.
1(10)
[DOI] 10.1371/journal.pdig.0000110.
[PMID] 36590701.
2022
Potentials and Challenges of Pervasive Sensing in the Intensive Care Unit.
Frontiers in digital health.
4
[DOI] 10.3389/fdgth.2022.773387.
[PMID] 35656333.
2022
The effect of non-pharmacologic strategies on prevention or management of intensive care unit delirium: a systematic review
F1000Research.
9
[DOI] 10.12688/f1000research.25769.3.
[PMID] 36110837.
2022
Uncertainty-aware deep learning in healthcare: A scoping review
PLOS Digital Health.
1(8)
[DOI] 10.1371/journal.pdig.0000085.
[PMID] 36590140.
2021
A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.
Frontiers in immunology.
12
[DOI] 10.3389/fimmu.2021.696536.
[PMID] 34484194.
2021
Advances in artificial intelligence and deep learning systems in ICU-related acute kidney injury.
Current opinion in critical care.
27(6):560-572
[DOI] 10.1097/MCC.0000000000000887.
[PMID] 34757993.
2021
Association of early initiation of dialysis with all-cause and cardiovascular mortality: A propensity score weighted analysis of the United States Renal Data System.
Hemodialysis international. International Symposium on Home Hemodialysis.
25(2):188-197
[DOI] 10.1111/hdi.12912.
[PMID] 33644974.
2021
Association of persistent acute kidney injury and renal recovery with mortality in hospitalised patients
BMJ Health & Care Informatics.
28(1)
[DOI] 10.1136/bmjhci-2021-100458.
[PMID] 34876451.
2021
Association of Postoperative Undertriage to Hospital Wards With Mortality and Morbidity.
JAMA network open.
4(11)
[DOI] 10.1001/jamanetworkopen.2021.31669.
[PMID] 34757412.
2021
Bridging the artificial intelligence valley of death in surgical decision-making
Surgery.
169(4):746-748
[DOI] 10.1016/j.surg.2021.01.008.
[PMID] 33608148.
2021
Building an Artificial Intelligence-Competent Surgical Workforce.
JAMA surgery.
156(6):511-512
[DOI] 10.1001/jamasurg.2021.0045.
[PMID] 33688933.
2021
Cardiovascular and Renal Disease in Chronic Critical Illness
Journal of Clinical Medicine.
10(8)
[DOI] 10.3390/jcm10081601.
[PMID] 33918938.
2021
Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors
Journal of Clinical Medicine.
10(15)
[DOI] 10.3390/jcm10153211.
[PMID] 34361995.
2021
Deep Multi-Modal Transfer Learning for Augmented Patient Acuity Assessment in the Intelligent ICU.
Frontiers in digital health.
3
[DOI] 10.3389/fdgth.2021.640685.
[PMID] 33718920.
2021
Development of a Theory-Informed Behavior Change Intervention to Reduce Inappropriate Prescribing of Nephrotoxins and Renally Eliminated Drugs.
The Annals of pharmacotherapy.
55(12):1474-1485
[DOI] 10.1177/10600280211009567.
[PMID] 33855858.
2021
Equity and Artificial Intelligence in Surgical Care.
JAMA surgery.
156(6):509-510
[DOI] 10.1001/jamasurg.2020.7208.
[PMID] 33625504.
2021
Intraoperative hypotension and complications after vascular surgery: A scoping review
Surgery.
170(1):311-317
[DOI] 10.1016/j.surg.2021.03.054.
[PMID] 33972092.
2021
Machine Learning Applications in Solid Organ Transplantation and Related Complications.
Frontiers in immunology.
12
[DOI] 10.3389/fimmu.2021.739728.
[PMID] 34603324.
2021
Metabolomic Profiling for Diagnosis and Prognostication in Surgery: A Scoping Review.
Annals of surgery.
273(2):258-268
[DOI] 10.1097/SLA.0000000000003935.
[PMID] 32482979.
2021
Optimizing predictive strategies for acute kidney injury after major vascular surgery.
Surgery.
170(1):298-303
[DOI] 10.1016/j.surg.2021.01.030.
[PMID] 33648766.
2021
Pain Action Unit Detection in Critically Ill Patients.
Proceedings : Annual International Computer Software and Applications Conference. COMPSAC.
2021:645-651
[DOI] 10.1109/compsac51774.2021.00094.
[PMID] 34723289.
2021
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative
Nature Reviews Nephrology.
17(9):605-618
[DOI] 10.1038/s41581-021-00418-2.
[PMID] 33976395.
2021
Pro Re Nata Antihypertensive Medications and Adverse Outcomes in Hospitalized Patients: A Propensity-Matched Cohort Study.
Hypertension (Dallas, Tex. : 1979).
78(2):516-524
[DOI] 10.1161/HYPERTENSIONAHA.121.17279.
[PMID] 34148363.
2021
Reinforcement learning in surgery
Surgery.
170(1):329-332
[DOI] 10.1016/j.surg.2020.11.040.
[PMID] 33436272.
2021
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Shock (Augusta, Ga.).
55(5):587-595
[DOI] 10.1097/SHK.0000000000001671.
[PMID] 33021571.
2021
The effect of non-pharmacologic strategies on prevention or management of intensive care unit delirium: a systematic review
F1000Research.
9
[DOI] 10.12688/f1000research.25769.2.
2021
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
35(2)
[DOI] 10.1096/fj.202002150R.
[PMID] 33140449.
2020
Added Value of Intraoperative Data for Predicting Postoperative Complications: The MySurgeryRisk PostOp Extension
Journal of Surgical Research.
254:350-363
[DOI] 10.1016/j.jss.2020.05.007.
[PMID] 32531520.
2020
Artificial Intelligence and Surgical Decision-making.
JAMA surgery.
155(2):148-158
[DOI] 10.1001/jamasurg.2019.4917.
[PMID] 31825465.
2020
Artificial intelligence approaches to improve kidney care
Nature Reviews Nephrology.
16(2):71-72
[DOI] 10.1038/s41581-019-0243-3.
[PMID] 31873197.
2020
Audiovisual Modules to Enhance Informed Consent in the ICU: A Pilot Study.
Critical care explorations.
2(12)
[DOI] 10.1097/CCE.0000000000000278.
[PMID] 33251517.
2020
Automated Detection of Rest Disruptions in Critically Ill Patients.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference.
2020:5450-5454
[DOI] 10.1109/EMBC44109.2020.9175252.
[PMID] 33019213.
2020
Cardiovascular death and progression to end-stage renal disease after major surgery in elderly patients
BJS Open.
4(1):145-156
[DOI] 10.1002/bjs5.50232.
[PMID] 32011817.
2020
Contemporary Management of Severe Acute Kidney Injury and Refractory Cardiorenal Syndrome: JACC Council Perspectives.
Journal of the American College of Cardiology.
76(9):1084-1101
[DOI] 10.1016/j.jacc.2020.06.070.
[PMID] 32854844.
2020
COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup
Nature Reviews Nephrology.
16(12):747-764
[DOI] 10.1038/s41581-020-00356-5.
[PMID] 33060844.
2020
Decision analysis and reinforcement learning in surgical decision-making.
Surgery.
168(2):253-266
[DOI] 10.1016/j.surg.2020.04.049.
[PMID] 32540036.
2020
Delayed interhospital transfer of critically ill patients with surgical sepsis.
The journal of trauma and acute care surgery.
88(1):169-175
[DOI] 10.1097/TA.0000000000002476.
[PMID] 31856021.
2020
Discovery and Validation of Urinary Molecular Signature of Early Sepsis.
Critical care explorations.
2(10)
[DOI] 10.1097/CCE.0000000000000195.
[PMID] 33063018.
2020
Human Activity Recognition Using Inertial, Physiological and Environmental Sensors: A Comprehensive Survey
IEEE Access.
8:210816-210836
[DOI] 10.1109/access.2020.3037715.
[PMID] 33344100.
2020
ICU Delirium-Prediction Models: A Systematic Review.
Critical care explorations.
2(12)
[DOI] 10.1097/CCE.0000000000000296.
[PMID] 33354672.
2020
Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study.
Intensive care medicine.
46(5):943-953
[DOI] 10.1007/s00134-019-05919-0.
[PMID] 32025755.
2020
Improving the Intensive Care Patient Experience With Virtual Reality-A Feasibility Study.
Critical care explorations.
2(6)
[DOI] 10.1097/CCE.0000000000000122.
[PMID] 32695991.
2020
Intelligent, Autonomous Machines in Surgery
Journal of Surgical Research.
253:92-99
[DOI] 10.1016/j.jss.2020.03.046.
[PMID] 32339787.
2020
Joint Distribution and Transitions of Pain and Activity in Critically Ill Patients.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference.
2020:4534-4538
[DOI] 10.1109/EMBC44109.2020.9176453.
[PMID] 33019002.
2020
Mysteries, Epistemological Modesty, and Artificial Intelligence in Surgery.
Frontiers in artificial intelligence.
2
[DOI] 10.3389/frai.2019.00032.
[PMID] 33117989.
2020
Opportunities for machine learning to improve surgical ward safety.
American journal of surgery.
220(4):905-913
[DOI] 10.1016/j.amjsurg.2020.02.037.
[PMID] 32127174.
2020
Pain and Physical Activity Association in Critically Ill Patients.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference.
2020:5696-5699
[DOI] 10.1109/EMBC44109.2020.9176227.
[PMID] 33019268.
2020
Publisher Correction: COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup
Nature Reviews Nephrology.
[DOI] 10.1038/s41581-020-00372-5.
[PMID] 33139940.
2020
Quality of care after AKI development in the hospital: Consensus from the 22nd Acute Disease Quality Initiative (ADQI) conference.
European journal of internal medicine.
80:45-53
[DOI] 10.1016/j.ejim.2020.04.056.
[PMID] 32616340.
2020
Reactive Artificial Intelligence Using Big Data in the Era of Precision Medicine-Reply.
JAMA surgery.
155(7):671-672
[DOI] 10.1001/jamasurg.2020.0856.
[PMID] 32374380.
2020
The effect of non-pharmacologic strategies on prevention or management of intensive care unit delirium: a systematic review
F1000Research.
9
[DOI] 10.12688/f1000research.25769.1.
2020
The impact of environmental risk factors on delirium and benefits of noise and light modifications: a scoping review
F1000Research.
9
[DOI] 10.12688/f1000research.25901.1.
2019
Artificial intelligence to predict AKI: is it a breakthrough?
Nature reviews. Nephrology.
15(11):663-664
[DOI] 10.1038/s41581-019-0203-y.
[PMID] 31506607.
2019
Comparing clinical judgment with the MySurgeryRisk algorithm for preoperative risk assessment: A pilot usability study
Surgery.
165(5):1035-1045
[DOI] 10.1016/j.surg.2019.01.002.
[PMID] 30792011.
2019
DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning
Scientific Reports.
9(1)
[DOI] 10.1038/s41598-019-38491-0.
[PMID] 30755689.
2019
Extended vertical lists for temporal pattern mining from multivariate time series.
Expert systems.
36(5)
[DOI] 10.1111/exsy.12448.
[PMID] 33162636.
2019
External Validation of the qSOFA Score in Emergency Department Patients With Pneumonia.
The Journal of emergency medicine.
57(6):755-764
[DOI] 10.1016/j.jemermed.2019.08.043.
[PMID] 31735660.
2019
Improved predictive models for acute kidney injury with IDEA: Intraoperative Data Embedded Analytics
PLOS ONE.
14(4)
[DOI] 10.1371/journal.pone.0214904.
[PMID] 30947282.
2019
Intelligent ICU for Autonomous Patient Monitoring Using Pervasive Sensing and Deep Learning.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-44004-w.
[PMID] 31142754.
2019
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Critical care (London, England).
23(1)
[DOI] 10.1186/s13054-019-2628-x.
[PMID] 31722736.
2019
MySurgeryRisk: Development and Validation of a Machine-learning Risk Algorithm for Major Complications and Death After Surgery.
Annals of surgery.
269(4):652-662
[DOI] 10.1097/SLA.0000000000002706.
[PMID] 29489489.
2019
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
Critical care medicine.
47(11):e919-e929
[DOI] 10.1097/CCM.0000000000003926.
[PMID] 31389840.
2019
Persistent inflammation and anemia among critically ill septic patients.
The journal of trauma and acute care surgery.
86(2):260-267
[DOI] 10.1097/TA.0000000000002147.
[PMID] 30489504.
2019
Quality Improvement Goals for Acute Kidney Injury.
Clinical journal of the American Society of Nephrology : CJASN.
14(6):941-953
[DOI] 10.2215/CJN.01250119.
[PMID] 31101671.
2019
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The Development of Chronic Critical Illness Determines Physical Function, Quality of Life, and Long-Term Survival Among Early Survivors of Sepsis in Surgical ICUs.
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Comparison of Gaussian Processes Methods to Linear methods for Imputation of Sparse Physiological Time Series.
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Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis
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Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis
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Grants
Sep 2023
ACTIVE
Computational Image Analysis of Renal Transplant Biopsies to Predict Graft Outcome
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Apr 2023
ACTIVE
Aligning Patient Acuity with Resource Intensity after Major Surgery
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2022
ACTIVE
Patient-Focused Collaborative Hospital Repository Uniting Standards (CHoRUS) for Equitable AI
Role: Principal Investigator
Funding: MASSACHUSETTS GENERAL HOSPITAL
via NATL INST OF HLTH OD
Aug 2022
ACTIVE
Explainable, Fair, Reproducible and Collaborative Surgical Artificial Intelligence: Integrating data, algorithms and clinical reasoning for surgical risk assessment (XAI-IDEALIST)
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Apr 2022
ACTIVE
(MEnD-AKI) Multicenter Implementation of an Electronic Decision Support System for Drug-Associated AKI
Role: Principal Investigator
Funding: UNIV OF PITTSBURGH MED CNTR
via NATL INST OF HLTH NIDDK
Jan 2022
ACTIVE
A Sample Collection Study to Validate the NEPHROCLEAR CCL14 Test
Role: Principal Investigator
Funding: ASTUTE MEDICAL
Sep 2021
ACTIVE
Informing the Emergency Care of Septic Shock Patients: A Novel Application of Data-Driven Analytics
Role: Other
Funding: NATL INST OF HLTH NIGMS
Jun 2021
ACTIVE
(MEnD-AKI) Multicenter Implementation of an Electronic Decision Support System for Drug-Associated AKI
Role: Principal Investigator
Funding: UNIV OF PITTSBURGH MED CNTR
via NATL INST OF HLTH NIDDK
May 2021
ACTIVE
ADAPT: Autonomous Delirium Monitoring and Adaptive Prevention
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Apr 2021
ACTIVE
Intelligent Intensive Care Unit (I2CU): Pervasive Sensing and Artificial Intelligence for Augmented Clinical Decision-making
Role: Principal Investigator
Funding: NATL INST OF HLTH NIBIB
Jan 2021
– Apr 2023
Advancing Racial Justice Through Inclusion, Diversity, Equity, and Access at the University of Florida
Role: Project Manager
Funding: UF RESEARCH
May 2020
ACTIVE
Development and Validation of Computational Algorithms to Assess Kidney Health in Electronic Health Records
Role: Other
Funding: NATL INST OF HLTH NIDDK
Mar 2020
ACTIVE
CTOA
Role: Principal Investigator
Funding: UNIV OF FLORIDA
Feb 2019
– Nov 2022
Autonomous Pain Recognition in Non-Verbal and Critically Ill Patients
Role: Co-Investigator
Funding: NATL INST OF HLTH NIBIB
Jun 2018
– May 2020
PICS: A New Horizon for Surgical Critical Care
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Feb 2018
– Feb 2021
STandard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI): A Multi-Centre, Randomized, Controlled Trial
Role: Principal Investigator
Funding: ST. MICHAELS HOSPITAL
via CANADIAN INST OF HLTH RES
Nov 2017
– Oct 2022
A Multi-Center, Randomized, Placebo-Controlled, Double-Blind Study To Confirm Efficacy And Safety Of Terlipressin In Subjects With Hepatorenal Syndrome Type 1
Role: Principal Investigator
Funding: INTL HEALTHCARE
via *MALLINCKRODT PHARMACEUTICALS-Bankrupt
Jun 2017
– May 2018
PICS: A New Horizon for Surgical Critical Care
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2016
– Jul 2018
214 Fund – AP-RECAP-AKI-02-01
Role: Principal Investigator
Funding: PPD DEVELOPMENT
Mar 2016
– Jul 2022
Integrating data, algorithms and clinical reasoning for surgical risk assessment
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Oct 2015
– Oct 2018
A Phase 3, Placebo-Controlled, Randomized, Double-Blind, Multi-Center Study of LJPC-501 in Patients with Catecholamine-Resistant Hypotension (CRH)
Role: Principal Investigator
Funding: LA JOLLA PHARMACEUTICAL CO
Jun 2015
– Jun 2018
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, THREE-ARM PARALLEL-GROUP, DOSE-FINDING, ADAPTIVE DESIGN PHASE-II-B …
Role: Principal Investigator
Funding: PPD DEVELOPMENT
via AM-PHARMA
Jun 2015
– May 2016
PICS: A New Horizon for Surgical Critical Care
Role: Project Manager
Funding: NATL INST OF HLTH NIGMS
May 2014
– Apr 2017
Network analysis of urinary molecular signature complements clinical data to predict postoperative acute kidney injury
Role: Principal Investigator
Funding: HEERMANN ANESTHESIA FOU, I
May 2013
– Mar 2016
Identification and Validation of Biomarkers of Acute Kidney Injury Recovery-Ruby
Role: Principal Investigator
Funding: ASTUTE MEDICAL
Oct 2010
– Oct 2016
Evaluation of novel Biomakrers from Acute III Patients at Risk for Acute Kidney Injury
Role: Principal Investigator
Funding: ASTUTE MEDICAL
Education
Master of Science – Health Sciences in Clinical Research
2011
·
University of Florida
Fellowship – Critical Care Medicine
2006
·
University of Florida
Residency – Internal Medicine
2005
·
University of Florida
Fellowship – Nephrology
2003
·
University of Florida
Medical Degree
1990
·
University of Sarajevo
Contact Details
Phones:
- Business:
- (352) 273-5995
Administrative Spec III:
Addresses:
- Business Mailing:
-
1600 SW ARCHER RD RM MG 07
PO Box 100224
MEDICAL SCIENCES BLDG
GAINESVILLE FL 32610 - Business Street:
-
UNIVERSITY OF FLORIDA
PO BOX 100224
DEPARTMENT OF MEDICINE
GAINESVILLE FL 32610