Autosomal dominant polycystic kidney disease (ADPCKD) is the most common genetic disorder leading to kidney damage. Somewhere between 4–10 of every 4000 individuals have this condition, and every person who has the genetic disorder will develop kidney disease, and possibly end-stage kidney disease requiring either kidney dialysis or kidney transplant.  ADPCKD can also lead to significant pain, kidney stones, kidney bleeding (hemorrhage), increased risk of stroke, and numerous other complications.  In addition, each of the siblings and children of patients with ADPCKD have a 50% chance of having this condition.  The Division of Nephrology, Hypertension and Renal Transplantation offers a specialized and comprehensive ADPCKD clinic providing state-of-the-art evaluation, including genetic testing, counseling, and treatment.  Early diagnosis and treatment can substantially slow the progression of kidney damage from ADPCKD and it decreases the complications and symptoms associated with it.