Yogesh M Scindia,
Assistant Professor
Department:
MD-PULMONARY MEDICINE
Business Phone:
(352) 273-8737
Business Email:
yogesh.scindia@ufl.edu
Teaching Profile
Courses Taught
2021-2024
GMS6140 Principles of Immunology
2022-2024
GMS6143 Cells of the Innate Immune System
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0001-6382-6289
Publications
2024
Animal models of lupus nephritis: the past, present and a future outlook.
Autoimmunity.
57(1)
[DOI] 10.1080/08916934.2024.2319203.
[PMID] 38477884.
2024
Functional consequence of Iron dyshomeostasis and ferroptosis in systemic lupus erythematosus and lupus nephritis.
Clinical immunology (Orlando, Fla.).
262
[DOI] 10.1016/j.clim.2024.110181.
[PMID] 38458303.
2024
Rusting from the inside: kidney-specific ferroportin deficiency and associated iron overload dictate susceptibility to acute kidney injury and fibrosis
American Journal of Physiology-Renal Physiology.
326(3):F497-F498
[DOI] 10.1152/ajprenal.00384.2023.
2023
COVID-19-associated pulmonary aspergillosis in immunocompetent patients: A virtual patient cohort study.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2022.07.18.500514.
[PMID] 35898340.
2023
COVID-19-associated pulmonary aspergillosis in immunocompetent patients: a virtual patient cohort study.
Journal of mathematical biology.
87(1)
[DOI] 10.1007/s00285-023-01940-6.
[PMID] 37306747.
2023
Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis.
Clinical immunology (Orlando, Fla.).
248
[DOI] 10.1016/j.clim.2022.109213.
[PMID] 36566913.
2023
Male kidney-specific BMAL1 knockout mice are protected from K+-deficient, high-salt diet-induced blood pressure increases
American Journal of Physiology-Renal Physiology.
325(5):F656-F668
[DOI] 10.1152/ajprenal.00126.2023.
[PMID] 37706232.
2023
Metformin Alleviates Diabetes-Associated Hypertension by Attenuating the Renal Epithelial Sodium Channel.
Biomedicines.
11(2)
[DOI] 10.3390/biomedicines11020305.
[PMID] 36830842.
2022
Aspergillus Utilizes Extracellular Heme as an Iron Source During Invasive Pneumonia, Driving Infection Severity.
The Journal of infectious diseases.
225(10):1811-1821
[DOI] 10.1093/infdis/jiac079.
[PMID] 35267014.
2022
Circadian rhythms and renal pathophysiology
Journal of Clinical Investigation.
132(3)
[DOI] 10.1172/jci148277.
2022
Computational Modeling of Macrophage Iron Sequestration during Host Defense against Aspergillus.
mSphere.
7(4)
[DOI] 10.1128/msphere.00074-22.
[PMID] 35862797.
2022
Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.
PloS one.
17(9)
[DOI] 10.1371/journal.pone.0274427.
[PMID] 36084115.
2022
Iron Inhibits the Translation and Activity of the Renal Epithelial Sodium Channel.
Biology.
11(1)
[DOI] 10.3390/biology11010123.
[PMID] 35053120.
2022
Labile iron accumulation augments T follicular helper cell differentiation
Journal of Clinical Investigation.
132(9)
[DOI] 10.1172/jci159472.
2022
Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus
Immunology Letters.
247:13-21
[DOI] 10.1016/j.imlet.2022.03.008.
2022
Multi-scale mechanistic modelling of the host defence in invasive aspergillosis reveals leucocyte activation and iron acquisition as drivers of infection outcome.
Journal of the Royal Society, Interface.
19(189)
[DOI] 10.1098/rsif.2021.0806.
[PMID] 35414216.
2021
A modular computational framework for medical digital twins
Proceedings of the National Academy of Sciences.
118(20)
[DOI] 10.1073/pnas.2024287118.
[PMID] 33972437.
2021
Iron Metabolism: An Under Investigated Driver of Renal Pathology in Lupus Nephritis.
Frontiers in medicine.
8
[DOI] 10.3389/fmed.2021.643686.
[PMID] 33912577.
2021
Neutrophil-Derived Tumor Necrosis Factor Drives Fungal Acute Lung Injury in Chronic Granulomatous Disease.
The Journal of infectious diseases.
224(7):1225-1235
[DOI] 10.1093/infdis/jiab188.
[PMID] 33822981.
2021
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
International journal of molecular sciences.
22(24)
[DOI] 10.3390/ijms222413255.
[PMID] 34948056.
2020
Circulating fibrocytes traffic to the lung in murine acute lung injury and predict outcomes in human acute respiratory distress syndrome: a pilot study.
Molecular medicine (Cambridge, Mass.).
26(1)
[DOI] 10.1186/s10020-020-00176-0.
[PMID] 32460694.
2020
Efficacy of the Combination of Metformin and CTLA4Ig in the (NZB × NZW)F1 Mouse Model of Lupus Nephritis
ImmunoHorizons.
4(6):319-331
[DOI] 10.4049/immunohorizons.2000033.
2020
Modulation of iron homeostasis with hepcidin ameliorates spontaneous murine lupus nephritis
Kidney International.
98(1):100-115
[DOI] 10.1016/j.kint.2020.01.025.
2020
Protective role of DJ-1 in endotoxin-induced acute kidney injury.
American journal of physiology. Renal physiology.
319(4):F654-F663
[DOI] 10.1152/ajprenal.00064.2020.
[PMID] 32715759.
2019
Iron Homeostasis in Healthy Kidney and its Role in Acute Kidney Injury.
Seminars in nephrology.
39(1):76-84
[DOI] 10.1016/j.semnephrol.2018.10.006.
[PMID] 30606409.
2019
Protective Role of Hepcidin in Polymicrobial Sepsis and Acute Kidney Injury.
Frontiers in pharmacology.
10
[DOI] 10.3389/fphar.2019.00615.
[PMID] 31244655.
2016
Biocompatibility of ferritin-based nanoparticles as targeted MRI contrast agents.
Nanomedicine : nanotechnology, biology, and medicine.
12(6):1735-45
[DOI] 10.1016/j.nano.2016.03.007.
[PMID] 27071333.
2015
Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis.
Journal of the American Society of Nephrology : JASN.
26(11):2800-14
[DOI] 10.1681/ASN.2014101037.
[PMID] 25788528.
2012
Activated CD4+ T cells target mesangial antigens and initiate glomerulonephritis.
Nephron. Experimental nephrology.
121(1-2):e1-9
[DOI] 10.1159/000342368.
[PMID] 23095207.
2011
Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren’s syndrome-like disease.
Oral diseases.
17(8):801-7
[DOI] 10.1111/j.1601-0825.2011.01839.x.
[PMID] 21815968.
2011
Deficiency of a transcriptional regulator, inhibitor of differentiation 3, induces glomerulonephritis in apolipoprotein E-deficient mice: a model linking hyperlipidemia and renal disease.
The American journal of pathology.
179(2):651-60
[DOI] 10.1016/j.ajpath.2011.04.029.
[PMID] 21801865.
2011
Novel therapeutic approaches to lupus glomerulonephritis: translating animal models to clinical practice.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
57(3):498-507
[DOI] 10.1053/j.ajkd.2010.10.052.
[PMID] 21239097.
2010
Mesangial pathology in glomerular disease: targets for therapeutic intervention.
Advanced drug delivery reviews.
62(14):1337-43
[DOI] 10.1016/j.addr.2010.08.011.
[PMID] 20828589.
2009
Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.
38(1):42-7
[DOI] 10.1111/j.1600-0714.2008.00700.x.
[PMID] 19192049.
2009
Genetic complementation results in augmented autoantibody responses to lupus-associated antigens.
Journal of immunology (Baltimore, Md. : 1950).
183(5):3505-11
[DOI] 10.4049/jimmunol.0901207.
[PMID] 19667095.
2008
Anti-alpha8 integrin immunoliposomes in glomeruli of lupus-susceptible mice: a novel system for delivery of therapeutic agents to the renal glomerulus in systemic lupus erythematosus.
Arthritis and rheumatism.
58(12):3884-91
[DOI] 10.1002/art.24026.
[PMID] 19035491.
2008
Colorimetric polymer films for predicting lipid interactions and percutaneous adsorption of pharmaceutical formulations.
Pharmaceutical research.
25(12):2815-21
[DOI] 10.1007/s11095-008-9650-z.
[PMID] 18581206.
2007
Colorimetric detection and fingerprinting of bacteria by glass-supported lipid/polydiacetylene films.
Langmuir : the ACS journal of surfaces and colloids.
23(8):4682-7
[PMID] 17371063.
2007
Studies on the optimisation of optical response of scintillating optodes
Sensors and Actuators B: Chemical.
123(1):50-58
[DOI] 10.1016/j.snb.2006.07.020.
2007
Study on physical and electrostatic interactions of counterions in poly(perfluorosulfonic) acid matrix: Characterization of diffusion properties of membrane using radiotracers
Electrochimica Acta.
52(19):5968-5974
[DOI] 10.1016/j.electacta.2007.03.044.
2005
Coupled-diffusion transport of Cr(VI) across anion-exchange membranes prepared by physical and chemical immobilization methods
Journal of Membrane Science.
249(1-2):143-152
[DOI] 10.1016/j.memsci.2004.10.015.
2005
Self-diffusion coefficient of water in Nafion-117 membrane with different monovalent counterions: a radiotracer study
Journal of Membrane Science.
250(1-2):39-45
[DOI] 10.1016/j.memsci.2004.10.013.
2004
Chemically selective membrane optode for Cr(VI) determination in aqueous samples
Analytica Chimica Acta.
515(2):311-321
[DOI] 10.1016/j.aca.2004.03.074.
2004
Isotopic and Ion-Exchange Kinetics in the Nafion-117 Membrane
The Journal of Physical Chemistry B.
108(13):4104-4110
[DOI] 10.1021/jp037058v.
Grants
Jul 2023
ACTIVE
Renewal: Pannexin-1 signaling in abdominal aortic aneurysms
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2023
– Dec 2023
VA IPA – Yogesh Scindia
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Apr 2023
ACTIVE
Targeting ferroptosis in renal tubular epithelial cells to improve outcomes of lupus nephritis
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Sep 2021
– Sep 2023
Efficacy of VIT-2763 in a mouse model of acute kidney injury (AKI)
Role: Principal Investigator
Funding: VIFOR (International) LTD
Dec 2020
– Jun 2023
Efficacy of VIT-2763 in a mouse model of lupus nephritis
Role: Principal Investigator
Funding: VIFOR (International) LTD
Contact Details
Phones:
- Business:
- (352) 273-8737
Emails:
- Business:
- yogesh.scindia@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100225
GAINESVILLE FL 32610 - Business Street:
-
1345 CENTER DR
GAINESVILLE FL 32611